GABAB-ergic motor cortex dysfunction in SSADH deficiency

The Ipsilateral Human Motor Cortex Can Functionally Compensate for Acute Contralateral Motor Cortex Dysfunction

What promotes motor recovery from stroke? To date, studies of recovery from stroke have shown alterations in function in various cortical areas, including the contralesional (unaffected) motor cortex (M1). However, whether these changes contribute to recovery or are mere epiphenomena remains unclear. We therefore sought evidence that the ipsilateral M1 can compensate for dysfunction of the cont...

Motor cortex dysfunction in complex regional pain syndrome.

OBJECTIVE Most patients with complex regional pain syndrome (CRPS) exhibit debilitating motor symptoms. The effect of continuous pain on motor system in CRPS, however, is not well known. We searched for signs of motor cortex dysfunction in chronic CRPS type 1 patients with motor impairment. METHODS We recorded rhythmic brain activity with magnetoencephalography (MEG) during noxious thulium-la...

SSADH deficiency in an adult: Venturing outside of the diagnostic box and inside of the registry.

Motor cortex stimulation enhances motor recovery and reduces peri-infarct dysfunction following ischemic insult.

Recovery of motor function following stroke is believed to be supported, at least in part, by functional compensation involving residual neural tissue. The present study used a rodent model of focal ischemia and intracortical microstimulation (ICMS) to examine the behavioral and physiological effects of cortical stimulation in combination with motor rehabilitation. Adult rats were trained to cr...

Motor Cortex

M1 has been identified in several mammals, but most information comes from monkeys, cats, raccoons, rats, and humans. In each, five characteristics serve to define M1: (1) electrical stimulation there evokes movements with relatively low levels of electrical current, usually less than needed in other cortical fields; (2) it lacks a clearly identifiable internal granular layer, layer 4, and ther...